MHRA guidance on understanding the Risks of Finasteride

8 May, 2024

Finasteride, a medication primarily used to treat enlarged prostate and male pattern hair loss, has long been hailed as a solution for those grappling with these conditions. However, recent reminders from the MHRA shed light on potential risks associated with its usage. In this article, we delve into the psychiatric and sexual side effects of finasteride, emphasising the importance of informed decision-making and regular monitoring when using this medication.

Understanding Psychiatric Side Effects 

While finasteride is generally well-tolerated, it’s crucial to acknowledge its potential to induce psychiatric side effects. These may include mood swings, depression, anxiety, and in rare cases, suicidal thoughts. While the occurrence of these side effects is relatively uncommon, individuals should remain vigilant and promptly report any concerning symptoms to their healthcare provider. 

The Lingering Effects: Sexual Side Effects 

One of the most notable concerns surrounding finasteride is its impact on sexual function. Studies have highlighted a link between finasteride usage and sexual side effects such as erectile dysfunction, decreased libido, and ejaculation disorders. What’s particularly concerning is that these effects may persist even after discontinuation of the medication, significantly impacting an individual’s quality of life and psychological well-being. 

Navigating the Decision: Informed Consent 

Given the potential risks associated with finasteride, it’s essential for healthcare providers to engage in thorough discussions with patients before prescribing this medication. Informed consent should encompass a comprehensive understanding of both the benefits and potential side effects of finasteride, empowering individuals to make educated decisions regarding their treatment options. 

Vigilance and Monitoring 

For individuals currently using finasteride, regular monitoring is paramount. Healthcare providers should remain attentive to any signs of psychiatric or sexual side effects, conducting periodic assessments to ensure patient safety and well-being. Open communication between patients and healthcare professionals is key, fostering an environment where concerns can be addressed promptly and effectively. 

Conclusion: Prioritising Patient Safety 

 While finasteride undeniably offers therapeutic benefits for certain medical conditions, it’s essential to approach its usage with caution and vigilance. By remaining informed about the potential risks, engaging in thorough discussions with healthcare providers, and prioritising regular monitoring, individuals can mitigate the likelihood of adverse effects and make informed decisions regarding their treatment journey. 

Access the full guidance

Finasteride: reminder of the risk psychiatric side effects and of sexual side effects (which may persist after discontinuation of treatment) – GOV.UK (www.gov.uk)

Read through some of our other resources here: Ashtons Resources – Improving quality and compliance in medicines management